Avian pathogenic Escherichia coli (APEC) causes colibacillosis in avian species, and recent reports have suggested APEC as a potential foodborne zoonotic pathogen. Herein, we discuss the virulence and pathogenesis factors of APEC, review the zoonotic potential, provide the current status of antibiotic resistance and progress in vaccine development, and summarize the alternative control. Avian pathogenic Escherichia coli (APEC) is one of the most economically devastating pathogens affecting the poultry industry. This group of extra-intestinal E. coli causes a variety of clinical conditions including airsacculitis and cellulitis. The economic impact of APEC is mainly due to mortality, slower growth rates, and carcass downgrading
Tsh was first identified in an avian pathogenic E. coli isolate and was found to confer mannose-resistant hemagglutinating property in E. coli K12 when expressed in it ( Provence and Curtiss, 1994 ). The association of Tsh with the lethality of avian E. coli isolates was determined in a later study Escherichia coli sfa+ strains isolated from poultry were serotyped and characterized by polymerase chain reaction (PCR) and amplified fragment length polymorphism (AFLP). Isolates collected from 12 Brazilian poultry farms mostly belonged to serogroup O6, followed by serogroups O2, O8, O21, O46, O78, O88, O106, O111, and O143 Abstraet- Avian pathogenic Escherichia cnli (APEC) cause aerosacculitis, polyserositis, septicemia and other mainly extraintestinal diseases in chickens, turkeys and other avian species
Avian pathogenic Escherichia coli (APEC), uropathogenic E. coli (UPEC), and newborn meningitis-causing E. coli (NMEC) establish infections in extraintestinal habitats (extraintestinal pathogenic E. coli; ExPEC) of different hosts Avian pathogenic Escherichia coli (APEC) is associated with extraintestinal infections in poultry causing a variety of diseases collectively known as colibacillosis. The host and bacterial factors influencing and/or responsible for carriage and systemic translocation of APEC inside the host are poorly understood. Identification of such factors could help in the understanding of its. Avian pathogenic Escherichia coli(APEC) are a leading cause of morbidity and mortality in poultry and exert significant economic and welfare costs. Infections are frequently associated with sudden death, salpingitis, peritonitis, pericarditis, perihepatitis, airsacculitis and with reduced yield, quality and hatching of eggs Acquisition of avian pathogenic Escherichia coli plasmids by a commensal E. coli isolate enhances its abilities to kill chicken embryos, grow in human urine, and colonize the murine kidney. Infection and Immunity, 74 (11), 6287-6292 Avian pathogenic Escherichia coli(APEC) is an important respiratory pathogen of poultry. Various virulence factors are responsible for determining the pathogenicity of these strains, and it is commonly believed they are encoded on large plasmids the strains carry
Avian colibacillosis is caused by a group of pathogens designated avian pathogenic Escherichia coli (APEC). Despite being known for over a century, avian colibacillosis remains one of the major endemic diseases afflicting the poultry industry worldwide. Autologous bacterins provide limited serotype- Avian pathogenic Escherichia coli (APEC) infection causes avian colibacillosis, which refers to any localized or systemic infection, such as acute fatal septicemia or subacute pericarditis and airsacculitis. The RfaH transcriptional regulator in E. coli is known to regulate a number of phenotypic traits Avian pathogenic Escherichia coli (APEC) are considered as the most common bacterial infection in poultry [ 1 ]. Manifestations of colibacillosis in avian species are diverse and are often differentiated by the main anatomical location of the lesions and/or the proposed pathogenesis Strains of avian pathogenic Escherichia coli (APEC), the common pathogen of avian colibacillosis, encounter reactive oxygen species (ROS) during the infection process. Superoxide dismutases (SODs), acting as antioxidant factors, can protect against ROS-mediated host defenses
Avian pathogenic Escherichia coli (APEC) is considered an outstanding pathogen for the poultry industry, due to several economic losses associated with chronic respiratory disease, septicemia, salpingitis, omphalitis, and embrionary death Avian pathogenic Escherichia coli (APEC) is the principle cause of colibacillosis affecting poultry. The main challenge to the poultry industry is antimicrobial resistance and the emergence of multidrug resistant bacteria that threaten the safety of the food chain. Risk factors associated with emergence of antimicrobial resistance among avian pathogenic E. coli were correlated with the. Avian pathogenic Escherichia coli (APEC) cause severe colibacillosis and respiratory illness in poultry resulting in large economic losses. APEC strains are classified into the extraintestinal pathogenic E. coli subgroup (ExPEC), which is phylogenetically distinct from commensal and intestinal pathogenic E. coli groups To identify traits that predict avian pathogenic Escherichia coli (APEC) virulence, 124 avian E. coli isolates of known pathogenicity and serogroup were subjected to virulence genotyping and phylogenetic typing. The results were analyzed by multiple-correspondence analysis. From this analysis, five genes carried by plasmids were identified as being the most significantly associated with highly.
Escherichia coli bacterium is common to many environments and there are over 150 different strains. Avian pathogenic E. coli (APEC) strains cause diseases in birds at various ages. The introduction of such strains to chicken respiratory trac Background Avian-pathogenic Escherichia coli (APEC) are pathogenic strains of E. coli that are responsible for one of the most predominant bacterial disease affecting poultry worldwide called avian colibacillosis. This study describes the genetic determinants implicated in antimicrobial resistance among APEC isolated from different broiler farms in Egypt. Methods A total of 116 APEC were. Avian pathogenic Escherichia coli (APEC) causes a variety of bacterial infectious diseases known as avian colibacillosis leading to significant economic losses in the poultry industry worldwide and restricting the development of the poultry industry. The development of efflux pumps is one important bacterial antibiotic resistance mechanism Colibacillosis caused by avian pathogenic Escherichia coli (APEC) is a devastating disease of poultry that results in multi-million-dollar losses annually to the poultry industry. Disease syndromes associated with APEC includes colisepticemia, cellulitis, air sac disease, peritonitis, salpingitis, omphalitis, and osteomyelitis among others. A total of 61 APEC isolates collected during the Fall. Escherichia coli strains causing avian colibacillosis and human neonatal meningitis, urinary tract infections, and septicemia are collectively known as extraintestinal pathogenic E. coli (ExPEC). Characterization of ExPEC strains using various typing techniques has shown that they harbor many similarities, despite their isolation from different host species, leading to the hypothesis that.
Avian pathogenic Escherichia coli (APEC) is a major cause of disease impacting animal health. The bone marrow is the reservoir of immature immune cells; however, it has not been examined to date for gene expression related to developmental changes (cell differentiation, maturation, programming) after APEC infection. Here, we study gene expression in the bone marrow between infected and non. Background Avian pathogenic Escherichia coli (APEC), an important extraintestinal pathogenic E. coli, causes colibacillosis, an acute and mostly systemic disease involving multiple organ lesions such as meningitis. Meningitis-causing APEC can invade the host central nervous system by crossing the blood-brain barrier (BBB), which is a critical step in the development of meningitis Pathotyping avian pathogenic Escherichia coli strains in Korea : Yong-Wun Jeong, 1 Tae-Eun Kim, 3 Jae-Hong Kim, 1, 2 and Hyuk-Joon Kwon 2 1 Laboratory of Avian Diseases, College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University, Seoul 151-742, Korea.: 2 Zoonotic Disease Institute (ZooDI), Seoul National University, Seoul 151-742, Korea Avian pathogenic Escherichia coli (APEC), an important extraintestinal pathogenic E. coli (ExPEC), causes colibacillosis, an acute systemic disease that involves multiple organ lesions including respiratory, digestive, vascular and nervous system diseases (Dziva & Stevens, 2008; Ewers et al., 2004). Previous studies have demonstrated that APEC.
Abstract. Infections with avian pathogenic Escherichia coli (APEC) cause colibacillosis, an acute and mostly systemic disease resulting in significant economic losses in poultry industry worldwide. Avian colibacillosis is a complex syndrome characterized by multiple organ lesions with airsacculitis and associated pericarditis, perihepatitis and. . Avian colibacillosis refers to any localized or systemic infection caused by Avian Pathogenic Escherichia coli (APEC) belonging to several serogroups; and remains one of the most prevalent bacterial diseases affecting the poultry industry worldwide .The disease causes mortality and morbidity on poultry farms leading to grave economic losses as the infected birds keep dying and.
Chickens are a major source of protein worldwide, yet infectious diseases continue to threaten the poultry industry. Avian pathogenic Escherichia coli (APEC), a subgroup of extraintestinal pathogenic E. coli (ExPEC), causes colibacillosis in chickens resulting in economic loss because of treatment, condemnation of products, and death. In this study, we evaluated a recombinant antigens (rAg. Escherichia coli (E. coli) is a commensal bacteria in human and animal intestine as well as a common zoonotic pathogen.Avian pathogenic E. coli (APEC) refers to E. coli strains that can cause extraintestinal diseases in chicken and other avian species .As a major bacterial pathogen in the poultry industry worldwide, APEC can cause typical colibacillosis in broiler chickens, such as. Extraintestinal pathogenic Escherichia coli (ExPEC) constitutes ongoing health concerns for women, newborns, elderly, and immunocompromised individuals due to increased numbers of urinary tract infections (UTIs), newborn meningitis, abdominal sepsis, and septicemia.E. coli remains the leading cause of UTIs, with recent investigations reporting the emergence of E. coli as the predominant cause. Avian pathogenic Escherichia coli (APEC), an extraintestinal pathogenic E. coli causing colibacillosis in birds, is responsible for significant economic losses for the poultry industry. Recently, we reported that the APEC pathotype was characterized by possession of a set of genes contained within a 94-kb cluster linked to a ColV plasmid, pAPEC-O2-ColV ABSTRACT. Avian pathogenic Escherichia coli (APEC) strains cause a great diversity of diseases in birds and are responsible for great economic losses in the avian industry. To date, several studies have been carried out to better understand the APEC pathogenesis for a possible development of tools which could prevent the economics losses caused by these strains
Escherichia coli infections known as colibacillosis constitute a considerable challenge to poultry farmers worldwide, in terms of decreased animal welfare and production economy. Colibacillosis is caused by avian pathogenic E. coli (APEC). APEC strains are extraintestinal pathogenic E. coli and have in general been characterized as being a genetically diverse population Maybe, in the near future, when the mechanisms of pathogenicity and the virulence factors of avian pathogenic E. coli strains come to be better understood, the meaning of the APEC population structure achieved with this technique could be better comprehended.TERMOS DE INDEXAÇÃO: Escherichia coli aviária, tipificação, REP-PCR
Avian pathogenic Escherichia coli (APEC) is one of the most economically damaging diseases affecting the poultry industry. This group of extra-intestinal E. coli causes a variety of clinical conditions including air-sacculitis and cellulitis. The economic impact of APEC is mainly due to mortality, slower growth rates and carcass downgrading Avian pathogenic Escherichia coli (APEC) causes economically significant infections in poultry. The genetic diversity of APEC and phylogenetic relationships within and between APEC and other pathogenic E. coli are not yet well understood. We used multilocus sequence typing (MLST), PCR-based phylogrouping and virulence genotyping to analyse 75. Avian Pathogenic Escherichia coli (APEC) is the contributing agent behind the avian infectious disease colibacillosis, which causes substantial fatalities in poultry industries that has a significant impact on the economy and food safety. Several virulence genes have been shown to be concomitant with the extraintestinal survival of APEC. This study investigates the antibiotic resistance. Recent studies showed that the APEC virulence Avian pathogenic Escherichia coli (APEC), a subgroup of types are better classiﬁed using combinations of virulence extraintestinal pathogenic E. coli (ExPEC) enters through associated genes as strains with combinations of certain different routes including respiratory and genital tracts virulence.
Extra-intestinal pathogenic Escherichia coli (ExPEC) represent an emerging pathogen, with pandemic strains increasingly involved in cases of urinary tract infections (UTIs), bacteremia, and meningitis. In addition to affecting humans, the avian pathotype of ExPEC, avian pathogenic E. coli (APEC), causes severe economic losses to the poultry industry Avian pathogenic Escherichia coli (APEC) is the leading cause of systemic infections in poultry worldwide and has a hidden threat to public health. Escherichia coli type three secretion system 2 (ETT2), similar to the Salmonella pathogenicity island SPI1, is widely distributed in APEC and associated with virulence. The function of YqeI, which is one of the hypothetical transcriptional. Avian-Pathogenic Escherichia coli Strains Are Similar to Neonatal Meningitis E. coli Strains and Are Able To Cause Meningitis in the Rat Model of Human Disease䌤 Kelly A. Tivendale,1 Catherine M. Logue,2 Subhashinie Kariyawasam,3 Dianna Jordan,4 Ashraf Hussein,5 Ganwu Li,1 Yvonne Wannemuehler,1 and Lisa K. Nolan1* Department of Veterinary. Avian Pathogenic Escherichia coli in Audouin gulls (Larus audouinii). Could they affect the surviving of the bird colonies? Antonio Camarda1, Elena Circella1, Davide Giovanardi2, Donato Pennelli3, Patrizia Battista1, Evelyn Campagnari2, Giordano Bruni1, Silvia Tagliabue3 1 Dipartimento di Sanità e Benessere degli Animali..
Avian pathogenic Escherichia coli (APEC), an extraintestinal pathogenic E. coli (ExPEC), is the causative agent of avian colibacillosis, a disease that causes huge economic losses in the poultry industry and is characterized by infection through respiratory tract colonization followed by bacteraemia. A previous study in our lab demonstrated that phiv142-3 enhanced the survival ability of APEC. The canary (Serinus canaria) is appreciated for its beautiful song, colors, and docile temperament and drives a lucrative business. However, diseases caused by avian pathogenic Escherichia coli (APEC) compromise the health of canaries, and the inadequate antimicrobial treatment can lead to the emergence of resistant strains. This study aimed to characterize 21 isolates of E. coli obtained from. Avian pathogenic Escherichia coli (APEC) is a common bacterial pathogen infecting chickens, resulting in economic losses to the poultry industry worldwide. In particular, APEC O1, one of the most common serotypes of APEC, is considered problematic due to its zoonotic potential. Therefore, many attempts have been made to develop an effective vaccine against APEC O1 Histomonosis in chickens often appears together with colibacillosis in the field. Thus, we have experimentally investigated consequences of the co-infection of birds with Histomonas meleagridis and avian pathogenic Escherichia coli (APEC) on the pathology, host microbiota and bacterial translocation from the gut. Commercial chicken layers were infected via oral and cloacal routes with lux. Nevertheless, avian pathogenic Escherichia coli (APEC) may play a role as single aetiological agent. Moreover, E. coli superinfection may increase the pathogenic attitude of mycoplasma or Chlamydophila psittaci in turkey (Van Loock et al., 2006).The presence of virulence-associated genes seems to be linked to the pathogenic attitude of the.
Introduction. Avian pathogenic strains of Escherichia coli (APEC) cause several forms of extraintestinal infections in poultry, such as omphalitis in embryos, salpingitis in laying hens, cellulitis (necrotic dermatitis) in broiler chickens, swollen head syndrome, and respiratory tract infections .In any of these examples, infection may become systemic Extraintestinal pathogenic Escherichia coli (ExPEC) strains of human and avian origin show similarities that suggest that the avian strains potentially have zoonotic properties. However, the phylogenetic relationships between avian and human ExPEC strains are poorly documented, so this possibility is difficult to assess. We used PCR-based phylotyping and multilocus sequence typing (MLST) to.
Avian Pathogenic Escherichia coli (APEC) is a pathogen that causes colibacillosis in poultry, including salpingitis, omphalitis, cellulitis, swollen head syndrome, coligranuloma yolk sac inflammation, and air sacs inflammation. APEC is a zoonotic strain which spread through raw meat and processed meat products of animals and birds Pathogenic Escherichia coli Based on Four Diagnostic Strategy for Identifying Avian MG1655 (10) and the nonpathogenic E. coli avian strain EC79 (16). Screening for the F17, afa, and eae encoding genes was performed using colony hybridization. The corresponding probes were obtained Introduction. Avian pathogenic Escherichia coli (APEC) are extraintestinal E. coli that cause systemic disease in poultry, collectively known as avian colibacillosis and associated with major economic losses in the poultry industry worldwide (Dho-Moulin & Fairbrother, 1999; Dziva & Stevens, 2008).Availability of experimental infection models in target hosts and the recently available complete. Colibacillosis caused by Avian Pathogenic E. coli (APEC) is a costly disease for the poultry industry worldwide, significantly affecting one of the world's cheapest sources of high-quality protein, resulting in morbidity, mortality, loss of production and carcass condemnation. For years, it has been recognized that the most common serogroups of APEC from disease were O1, O2, and O78
Avian pathogenic Escherichia coli (APEC) is a facultative intracellular pathogen, and intracellular persistence in macrophages is essential for APEC extraintestinal dissemination. Until now, there is still no systematic interpretation of APEC intracellular proliferation. Intracellular survival factors, especially involved in pathometabolism, need to be further revealed Avian pathogenic Escherichia coli (APEC) is the causal agent of colibacillosis, one of the most common bacterial infections in the poultry sector. Antimicrobial susceptibility testing (AST) is essential for rational and prudent antimicrobial therapy. Subsequently, uniformity in test results from the various testing methodologies used in diagnostic laboratories is pivotal
Escherichia coli causing infection outside the gastrointestinal system are referred to as extra-intestinal pathogenic E. coli. Avian pathogenic E. coli is a subgroup of extra-intestinal pathogenic E. coli and infections due to avian pathogenic E. coli have major impact on poultry production economy and welfare worldwide. An almost definin Avian pathogenic Escherichia coli (APEC) infection causes severe respiratory and systemic diseases in poultry, resulting in serious losses to the poultry industry worldwide .Elucidation of the underlying molecular mechanisms of APEC pathogenicity is crucial for controlling avian colibacillosis. The pathogenicity of APEC is determined by many factors, such as virulence factors, secretion.
Tivendale, K. A. et al. Avian-pathogenic Escherichia coli strains are similar to neonatal meningitis E. coli strains and are able to cause meningitis in the rat model of human disease. Infect. ABSTRACT. Avian pathogenic Escherichia coli (APEC) is a subgroup of extra-intestinal pathogenic E. coli (ExPEC) strains that cause avian colibacillosis, resulting in significant economic losses to the poultry industry worldwide. It has been reported that a few two-component signal transduction systems (TCS) participate in the regulation of the virulence factors of APEC infection Avian pathogenic Escherichia coli (APEC) causes high mortality in poultry flocks and often is complicated with viral infections, leading to large economic losses; however, little information is available on the epidemiological characteristics of this pathogen in ducks. Therefore, a systemic epidemiological investigation was performed on 325. Avian pathogenic E. coli (APEC) are associated with extraintestinal diseases in poultry. The pstSCAB-phoU operon belongs to the Pho regulon and encodes the phosphate specific transport (Pst) system. A functional Pst system is required for full virulence in APEC and other bacteria and contributes to resistance of APEC to serum, to cationic antimicrobial peptides and acid shock
The Pap (pyelonephritis-associated pilus) or P fimbria is considered to be an important virulence marker of extraintestinal pathogenic Escherichia coli (ExPEC), a group of E. coli that includes avian pathogenic E. coli (APEC) and are responsible for a diverse spectrum of extraintestinal diseases in poultry 42,46.These fimbriae are encoded by the pap gene cluster which consists of 11 genes. The present study has determined the serological diversity, virulence-gene profile and in vitro antibiogram of avian pathogenic Escherichia coli (APEC) isolates from broiler chickens in India suspected to have died of colibacillosis. The virulence-gene profile of APEC was compared with that of the Escherichia coli isolates from faeces of apparently healthy chickens, called avian faecal E. coli.
Avian pathogenic Escherichia coli (APEC) causes avian colibacillosis, which results in economic and welfare costs in the poultry industry worldwide. The pathogenesis of avian pathogenic E. coli strains is not well defined. Here, the function of an outer membrane protein encoded by the ireA gene of avian pathogenic E. coli strain DE205B was investigated Avian pathogenic Escherichia coli (APEC) cause colibacillosis, a complex of respiratory and systemic diseases that exert substantial welfare and economic costs on poultry producers worldwide. Losses are incurred through premature deaths, condemnation of carcasses at slaughter, reduced productivity and recurring costs associated with antibiotic prophylaxis and therapy Avian pathogenic Escherichia coli (APEC) are responsible for heavy economic losses in poultry industry. Here we investigate DNA methylome of spleen and identify functional DNA methylation changes. The association of Escherichia coli strains with disease conditions in avian species was recognized over a century ago (cited by Sojka & Carnaghan, 1961), but these strains were never accorded a special status. Today, E. coli strains causing systemic disease in poultry (avian colibacillosis) are termed avian pathogenic E. coli (APEC)
Avian Pathol. 2021 May 28:1-151. doi: 10.1080/03079457.2021.1915960. Online ahead of print.ABSTRACTAvian Pathogenic E. coli (APEC) is the causative agent of avian colibacillosis, resulting in economic losses to the poultry industry through morbidity, mortality and carcass condemnation, and impacts the welfare of poultry Extraintestinal Pathogenic E. coli (ExPEC), are responsible for host diseases such as Neonatal Meningitis Escherichia coli (NMEC), the second-leading cause of neonatal bacterial meningitis, Avian Pathogenic E. coli (APEC), a cause of extraintestinal disease in poultry, and Uropathogenic E. coli (UPEC), the most common cause of urinary tract infections Avian pathogenic Escherichia coli is a group of ExPEC strains that cause several infectious processes termed colibacillosis, representing the major cause of losses in the poultry industry, resulting in decreased egg production, influencing the cost of treatment, and impacting carcasses condemnations and mortality. APEC strains can trigger. SUMMARY. Avian pathogenic strains of Escherichia coli cause a number of extraintestinal diseases in poultry, including airsacculitis and colisepticemia. Expression of 078 lipopoly-saccharide (LPS) is frequently associated with pathogenic isolates. Salmonella, a common poultry contaminant, is a major public health concern. The purpose of this.
Avian colibacillosis is caused by a group of pathogens designated avian pathogenic Escherichia coli (APEC). Despite being known for over a century, avian colibacillosis remains one of the major endemic diseases afflicting the poultry industry worldwide. Autologous bacterins provide limited serotype-specific protection, yet multiple serogroups. Avian pathogenic Escherichia coli (APEC) is detrimental to poultry health and its zoonotic potential is a food safety concern. Regulation of antimicrobials in food-production animals has put greater focus on enhancing host resistance to bacterial infections through genetics. To better define effective mechanism of host resistance, global gene expression in the spleen of chickens, harvested at.
Avian pathogenic Escherichia coli (APEC) is an important respiratory pathogen of poultry. A variety of virulence-associated genes and serogroups are associated with avian colibacillosis caused by APEC strains. One hundred forty-eight E. coli isolates recovered from diagnosed cases of avian colibacillosis from Guangdong province between 2005 and 2008 were serotyped, and characterized for. One hundred and twenty 30-day-old specific-pathogen-free chickens were inoculated with the liposomal inactivated avian pathogenic Escherichia coli (APEC) vaccine by eye drop or coarse spraying. All of the chickens produced anti-lipopolysaccharide antibodies of the IgG subclass in their sera as well as IgA antibodies in their oral mucus. The results demonstrated a rise in antibodies in the. Avian pathogenic E. coli (APEC) infections cause significant economic losses to the poultry industry worldwide Disease caused by APEC, is the leading cause of condemnation of broilers at time of slaughter that has increase by 15-fold since 1998. Economic losses due to cellulitis caused by APEC alone may exceed $40 million per year in the United States Extraintestinal infection with avian pathogenic Escherichia coli (APEC) induces colibacillosis in chickens. It is characterized by polyserositis, septicemic shock, and cellulitis and is responsible for enormous economic losses and frequent antibiotic treatment (1, 4, 11, 15).The spread of antibiotic resistance among bacteria has been recognized as an increasing problem in the veterinary and. Extraintestinal pathogenic (ExPEC) Escherichia coli strains of serotype O18:K1:H7 are mainly responsible for neonatal meningitis and sepsis in humans and belong to a limited number of closely related clones. The same serotype is also frequently isolated from the extraintestinal lesions of colibacillosis in poultry, but it is not well known to what extent human and avian strains of this. Avian pathogenic Escherichia coli (APEC), a pathotype of extraintestinal pathogenic E. coli, causes one of the most serious infectious diseases of poultry and shares some common virulence genes with neonatal meningitis-associated E. coli.TonB-dependent receptors (TBDRs) are ubiquitous outer membrane β-barrel proteins; they play an important role in the recognition of siderophores during iron.